Arthrospira platensis (synonym: Spirulina platensis) has a wide range of activities, notably antibacterial property against bacterial pathogens. Therefore, they can be considered as functional components in natural alternatives to antibiotics. The current study aims to evaluate the antibacterial and antioxidant potentials of S. platensis extract against different bacteria isolates isolated from wound infections, and food sources. The extraction of spirulina was performed using a variety of solvents including 70% ethanol, 70% methanol, and cold and hot distillation water. Ethanolic extracts of Spirulina showed higher antimicrobial activity than methanolic extracts using agar well diffusion method, with inhibition zones ranging from 22.67 to 38.67 mm. The most resistant bacterial isolate was identified using 16s rRNA gene sequencing as P. aeruginosa with GenBank accession no. NR_114471. Moreover, the antioxidant activity of Spirulina extracts was performed using DPPH radical scavenging activity. The results showed that aqueous hot extract of Spirulina recorded high levels of antioxidant activity after 72 hr (81.78±2.19). As a conclusion, in vitro results of antibacterial activity of spirulina extracts proved that S. platensis could be of potential value in production of antimicrobial agents which could be effective when compared with contemporary antimicrobial compounds. Hot water extracts from S. platensis had high potential of antioxidant activity in vitro and it can be used as natural antioxidants.
Rageh, N., Elballat, E., Elsilk, S., & Elsheikh, M. (2025). In Vitro Assessment of the Antimicrobial and Antioxidant Properties of Spirulina platensis Extracts Against Diverse Bacterial Isolates. Delta Journal of Science, 50(1), 129-146. doi: 10.21608/djs.2025.392378.1217
MLA
Nada Rageh; Enas Elballat; Sobhy Elsawy Elsilk; Mostafa Elsheikh. "In Vitro Assessment of the Antimicrobial and Antioxidant Properties of Spirulina platensis Extracts Against Diverse Bacterial Isolates", Delta Journal of Science, 50, 1, 2025, 129-146. doi: 10.21608/djs.2025.392378.1217
HARVARD
Rageh, N., Elballat, E., Elsilk, S., Elsheikh, M. (2025). 'In Vitro Assessment of the Antimicrobial and Antioxidant Properties of Spirulina platensis Extracts Against Diverse Bacterial Isolates', Delta Journal of Science, 50(1), pp. 129-146. doi: 10.21608/djs.2025.392378.1217
VANCOUVER
Rageh, N., Elballat, E., Elsilk, S., Elsheikh, M. In Vitro Assessment of the Antimicrobial and Antioxidant Properties of Spirulina platensis Extracts Against Diverse Bacterial Isolates. Delta Journal of Science, 2025; 50(1): 129-146. doi: 10.21608/djs.2025.392378.1217