Saponin ameliorate diabetes in STZ-diabetic rats

Document Type : Research and Reference

Authors

1 Biochemistry Division, Chemistry Department, Faculty of Science, Tanta University, Tanta, Egypt

2 Biochemistry Department, Faculty of Veterinary medicine, Benha University, Benha, Egypt

3 Zoology Department, Faculty of Science, Tanta University, Tanta, Egypt

4 Chemistry Department, Faculty of Science, Tanta University, Tanta, Egypt

Abstract

Saponins exhibit a wide spectrum of biological activities. Hyperglycemia
was induced by STZ. Saponin extract(300 mg/kg B.wt.) was administrated to STZdiabetic
rats. Saponin extract significantly reduced serum blood glucose, cholesterol,
triacylglycerol, liver L-MDA and significantly increased serum insulin level, In
conclusion, saponin has antidiabetic effect on STZ- diabetic rats.

Keywords